Medicines losing patent protection

MonthYear

December 2026

4 medicines lose their last listed patent or exclusivity in December 2026.

Dec 2Clindesseclindamycin phosphate · Padagis US LLC
Dec 7Protonixpantoprazole sodium · Wyeth Pharmaceuticals LLC
Dec 14Signiforpasireotide diaspartate · Recordati Rare Diseases Inc
Dec 20Tissuebluebrilliant blue G · Dutch Ophthalmic Research Center International BV

Dates are the patent and exclusivity end dates listed in the FDA's Orange Book, in its data up to October 9, 2026. Patents can be extended, challenged in court or settled, so a generic may come earlier, later or not at all. This is not legal or medical advice.

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